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Filtered Search Results
Medchemexpress LLC Amine-PEG3-lys(PEG3-N3)-PEG3-N3 | 2244602-35-3 | 98.0% | 750.84 g/mol | C30H58N10O12 | 50 MG
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Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched polyethylene glycol (PEG)-based linker with an amine terminus and azide functional groups. It is designed for use in antibody-drug conjugate (ADC) synthesis and general bioconjugation workflows where orthogonal azide chemistry and an amine handle are required.
- Branched PEG linker with amine and azide handles.
- Suitable for azide-alkyne click chemistry and amine coupling.
- High purity (98.0%).
- Available in multiple pack sizes, including 50 MG.
- Appearance: yellow to brown oil; stored at -20°C (pure) or -80°C in solvent for extended stability.
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Medchemexpress LLC Azide-PEG-amine | 95.0% | 100 MG
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Azide-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This molecule functions as a versatile click chemistry reagent, enabling crucial reactions in chemical biology and drug discovery.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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eMolecules 1368352-40-2 | ChemScene | 5-Bromo-4-ethylpyridin-2-amine | 100mg | 784458588 | CS-0334320 | MFCD22058625 | 201.067 | C7H9BrN2
Ambeed | (R)-2-Methylpiperidine | 250mg | 714088317 | A737468 | 1722-95-8 | MFCD01862168 | 99.177 | C6H13N
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eMolecules 5622-36-6 | Pharmablock | methyl 2-(quinolin-6-yl)acetate | 25mg | 721310743 | PBJZHC048 | MFCD04038669 | 201.225 | C12H11NO2
Pharmablock | methyl 2-(quinolin-6-yl)acetate | 25mg | 721310743 | PBJZHC048 | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2
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Medchemexpress LLC Mpeg-amine (MW 1000) | 80506-64-5 | 99.19% | (C2H4O)nC3H9NO | 100 MG
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m-PEG-NH2 (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates degradation of target proteins
- Utilizes the ubiquitin-proteasome system
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Medchemexpress LLC 5-Bromoisoquinoline | 34784-04-8 | 208.058 | 1 G
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5-Bromoisoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also a synthetic intermediate useful for pharmaceutical synthesis.
- Used as a biochemical reagent
- Applicable as a biological material
- Suitable as an organic compound for life science research
- Functions as a synthetic intermediate for pharmaceuticals
- Store in a cool, dry, and well-ventilated place
- Keep container tightly closed
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Medchemexpress LLC 3,6,9-trioxa-12-azaheptadecan-17-oic acid, folate conjugate | 710323-40-3 | 99.7% | 615.64 | C27H37N9O8 | 10 MG
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Folate-PEG3-amine is a cleavable three-unit polyethylene glycol linker bearing a folate moiety, used for targeted conjugation and antibody-drug conjugate synthesis. It provides a hydrophilic spacer with an amine for coupling to drugs or biomolecules.
- cleavable three-unit PEG spacer
- folate targeting motif for receptor-mediated delivery
- primary amine functional group for easy coupling
- high purity suitable for research applications
- hydrophilic spacer to improve solubility and reduce aggregation
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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | MFCD09752883 | 99.3% | C16H36N2O7 | 1 G
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Amino-PEG7-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by leveraging the intracellular ubiquitin-proteasome system, utilizing two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other a specific protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective protein degradation
- Applicable in cancer targeted therapy
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Medchemexpress LLC Amine-PEG3-desthiobiotin | 2237234-71-6 | 99.9% | C18H36N4O5 | 10MG
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Amine-PEG3-Desthiobiotin is a PEG-based bifunctional linker combining a short PEG3 spacer, a terminal primary amine, and a desthiobiotin affinity tag. It is designed for PROTAC assembly, bioconjugation, and affinity-capture workflows where reversible binding to streptavidin/avidin aids purification and enrichment.
- Terminal primary amine for efficient coupling to carboxyl or activated ester functionalities.
- Desthiobiotin tag enables reversible affinity capture with streptavidin/avidin systems.
- PEG3 spacer improves solubility and reduces steric hindrance between binding partners.
- High chemical purity suitable for synthetic and analytical applications.
- Available in multiple small-scale quantities to support method development and optimization.
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Medchemexpress LLC 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido- | 1800414-71-4 | MFCD08274605 | >98.0% | C24H50N4O11 | 100 MG
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Azido-PEG11-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group and an amine group. The product appears as a colorless to light yellow liquid and is intended for research use only, not for medical applications.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an azide group and an amine group
- Colorless to light yellow liquid
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Ambeed | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 5g | 525052806
7-Bromoisoquinoline | Ambeed | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 5g | 525052806
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | MFCD03453246 | ≥97.0% | C22H46N4O10 | 5 G
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Utilized in the synthesis of PROTACs
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eMolecules 5622-36-6 | Methyl 2-(quinolin-6-yl)acetate | Ambeed | MFCD04038669 | 201.225 | C12H11NO2 | 98.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 525134285
Methyl 2-(quinolin-6-yl)acetate | Ambeed | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 98.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 525134285
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TARGETMOL CHEMICALS INC 8-Chloroadenosine 5MG
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Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Chloroadenosine (NSC-354258) is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226, and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells. 8-Chloroadenosine (NSC-354258) has been shown to deplete ATP and inhibit tumor growth in hematological malignancies as well as in lung and breast cancer cell lines. Purity 99.48%
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Medchemexpress LLC Mal-C6-amine (TFA) | 731862-92-3 | MFCD11519191 | 99.7% | 310.27 g/mol | C12H17F3N2O4 | 1 G
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Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker supplied as the trifluoroacetate salt. It contains maleimide and aminohexyl functionalities designed for use in PROTAC and bioconjugate synthesis, providing compatibility with common coupling chemistries and formulation protocols for research applications.
- Alkyl chain linker suitable for PROTAC synthesis.
- Maleimide and amine functional groups for versatile conjugation.
- High reported purity (>99%) for reproducible results.
- Available in multiple pack sizes, including 1 g.
- Soluble in DMSO; in vivo formulation protocols provided.
- Storage and stability guidance provided for solid and solution forms.
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