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Filtered Search Results
Medchemexpress LLC Methyl 3,3-dimethoxypropionate | 7424-91-1 | MFCD00010650 | ≥98.0% | 148.16 g/mol | C6H12O4 | 250 G
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Methyl 3,3-dimethoxypropionate is an organic methyl ester used as a reagent and synthetic intermediate in organic and medicinal chemistry. The molecule features a dimethoxy (acetal)-protected propionate unit that acts as a masked aldehyde equivalent, enabling controlled deprotection and further functionalization. It is supplied as a colorless liquid at research-grade purity for laboratory synthesis and method development.
- Functions as a masked aldehyde equivalent in synthesis.
- Provides an acetal-protected propionate for selective transformations.
- Facilitates ester hydrolysis and downstream derivatization.
- Suitable for multistep organic and medicinal chemistry workflows.
- Available in research-scale quantities with high purity.
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC Pomalidomide-amido-C1-Br | 2351106-38-0 | MFCD32903493 | >98.0% | C15H12BrN3O5 | 10MG
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Pomalidomide-amido-C1-Br is an E3 ligase ligand-linker conjugate that incorporates a pomalidomide-based cereblon ligand for use in targeted protein degradation and PROTAC research. The compound is supplied as a high-purity research reagent (CAS 2351106-38-0) with molecular formula C15H12BrN3O5 and molecular weight 394.18 g·mol⁻¹. It is typically provided in milligram-scale quantities for screening and synthetic applications.
- High purity suitable for biochemical research.
- Contains a pomalidomide-based cereblon ligand for PROTAC design.
- Provided in small milligram-scale pack sizes for screening and synthesis.
- Characterized by molecular formula and molecular weight for identity confirmation.
- Supports design and development of E3 ligase recruiting degraders.
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=O | 250mg | 517090861](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000129387.jpg-250.jpg)
eMolecules 79025-28-8 | 3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861
3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | 79025-28-8 | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861
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![eMolecules 82121-05-9 | 7-Methoxy-4(1H)-quinolinone | Chem-Impex | MFCD11501414 | 175.187 | C10H9NO2 | 98.000 | COc1ccc2c(c1)[nH]ccc2=O | 1g | 112750550](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-112750550.PNG-250.jpg)
eMolecules 82121-05-9 | 7-Methoxy-4(1H)-quinolinone | Chem-Impex | MFCD11501414 | 175.187 | C10H9NO2 | 98.000 | COc1ccc2c(c1)[nH]ccc2=O | 1g | 112750550
7-Methoxy-4(1H)-quinolinone | Chem-Impex | 82121-05-9 | MFCD11501414 | 175.187 | C10H9NO2 | 98.000 | COc1ccc2c(c1)[nH]ccc2=O | 1g | 112750550
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Medchemexpress LLC 7-Hydroxycarbostyril | 70500-72-0 | 99.1% | 161.16 | 10 G
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7-Hydroxycarbostyril (synonyms: 7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline) is a quinolinone derivative. It can be used for the synthesis of Brexpiprazole, an orally active antipsychotic agent that acts as a partial agonist of human 5-HT1A and dopamine D2L receptors. This product is for research use only and not sold to patients.
- Quinolinone derivative
- Used for synthesis of Brexpiprazole
- Brexpiprazole acts as a partial agonist of human 5-HT1A and dopamine D2L receptors
- For research use only
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![eMolecules 63430-98-8 | (S)-1,2,3,4-Tetrahydro-quinoline-2-carboxylic acid hydrochloride | Combi-Blocks, Inc. | MFCD08436157 | 213.660 | C10H12ClNO2 | 97.000 | Cl.OC(=O)[C@@H]1CCc2ccccc2N1 | 1g | 603151238](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502189086.JPG-250.jpg)
eMolecules 63430-98-8 | (S)-1,2,3,4-Tetrahydro-quinoline-2-carboxylic acid hydrochloride | Combi-Blocks, Inc. | MFCD08436157 | 213.660 | C10H12ClNO2 | 97.000 | Cl.OC(=O)[C@@H]1CCc2ccccc2N1 | 1g | 603151238
(S)-1,2,3,4-Tetrahydro-quinoline-2-carboxylic acid hydrochloride | Combi-Blocks, Inc. | 63430-98-8 | MFCD08436157 | 213.660 | C10H12ClNO2 | 97.000 | Cl.OC(=O)[C@@H]1CCc2ccccc2N1 | 1g | 603151238
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Medchemexpress LLC Ro 31-9790 | 145337-55-9 | 99.4% | 315.41 g·mol⁻1 | C15H29N3O4 | 5 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor (synonym GI4747) used in biochemical and cellular research to probe MMP activity and L-selectin shedding. It is supplied as a solid (off-white to light yellow) and is available in solution form for convenience. The compound is characterized by its molecular formula C15H29N3O4 and high vendor-reported purity, and is typically used for in vitro and preclinical studies.
- High purity (≈99.4%) suitable for analytical and biological assays.
- Solid form, off-white to light yellow, with solution option in DMSO (10 mM, 1 mL).
- Available in multiple package sizes down to milligram quantities for small-scale experiments.
- Effective inhibitor for studying matrix metalloproteinase activity and L-selectin shedding.
- Provided with safety data and characterization documents for research use.
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Medchemexpress LLC Interleukin-31 (canine) | >95.0% | 20UG
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Recombinant canine interleukin-31 expressed in HEK293 mammalian cells and supplied as a lyophilized N-His-tagged protein for research use. The product is provided as a stabilized lyophilized powder formulated in PBS with trehalose, exhibits glycosylation-dependent mobility on SDS-PAGE, and should be stored frozen and handled per supplier recommendations to preserve activity.
- Produced in HEK293 mammalian cells for native-like glycosylation.
- Contains N-terminal His tag to enable purification and detection.
- Lyophilized powder stabilized with trehalose for storage and shipping.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Molecular weight approximately 26-36 kDa due to glycosylation.
- Reconstitute and store according to supplier recommendations to preserve activity.
- For research use only; not for clinical or diagnostic applications.
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Medchemexpress LLC Pomalidomide-amido-C | 25MG
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Pomalidomide-amido-C | 25MG
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Sigma Aldrich Fine Chemicals Biosciences Ethyl 2 trans 4 cis decadi1KG
Ethyl 2 trans 4 cis decadi1KG
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Medchemexpress LLC Al-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 10MG
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AL-611 is a research-grade small-molecule inhibitor described by the manufacturer as an HCV protease inhibitor intended for laboratory research use. It is supplied as a white to off-white solid and is characterized by a high reported purity and defined molecular properties.
- Potent HCV protease inhibitor for laboratory research.
- High purity (99.93%).
- White to off-white solid, suitable for analytical and biological assays.
- Molecular weight 614.54 Da; molecular formula C25H33F2N6O8P.
- Datasheet, certificate of analysis, and safety data sheet available.
- Intended for research use only, not for human or veterinary use.
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TARGETMOL CHEMICALS INC KRM-III 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation with an IC50 of approximately 5 uM. purity: 99%
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TARGETMOL CHEMICALS INC CONIVAPTAN HYDROCHLORIDE 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist used in the therapy of hypervolemic hyponatremia and euvolemic. purity: 99%
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Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 10 G
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1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM. It appears as a solid below 26°C and a liquid above 29°C, with a colorless to off-white appearance. It is soluble in water at ≥ 100 mg/mL (767.87 mM).
- Deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM
- Appears as a solid below 26°C and a liquid above 29°C
- Colorless to off-white appearance
- Soluble in water at ≥ 100 mg/mL
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